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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS16
All Species:
14.85
Human Site:
S273
Identified Species:
36.3
UniProt:
Q8TE57
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE57
NP_620687.2
1224
136203
S273
I
L
P
D
E
Y
K
S
C
L
R
H
K
R
S
Chimpanzee
Pan troglodytes
XP_526829
1072
119415
K190
L
P
S
H
L
S
W
K
L
G
R
A
A
Q
G
Rhesus Macaque
Macaca mulatta
XP_001082662
1224
136022
S273
I
L
P
D
E
Y
K
S
C
L
R
H
K
R
S
Dog
Lupus familis
XP_545184
1278
141611
S327
I
L
P
D
E
Y
A
S
C
L
R
R
K
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z28
1222
136264
P271
I
L
P
D
E
Y
K
P
S
S
R
H
K
R
S
Rat
Rattus norvegicus
Q1EHB3
1595
175796
S246
H
G
Q
P
Q
V
E
S
Y
V
L
T
I
M
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511434
1195
134964
Y244
I
L
P
D
E
Y
K
Y
P
L
R
K
K
R
S
Chicken
Gallus gallus
XP_424749
1118
125075
N234
F
P
T
S
L
P
V
N
D
T
L
S
S
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919066
1234
137743
Q282
V
M
P
D
E
F
E
Q
Q
I
R
V
K
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780466
1202
135114
T258
A
N
G
S
S
I
Q
T
R
K
R
R
S
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
97.7
81.4
N.A.
82.6
30.5
N.A.
76.6
35.7
N.A.
56.4
N.A.
N.A.
N.A.
N.A.
46.3
Protein Similarity:
100
87.3
98.4
87
N.A.
89
43
N.A.
84.9
53.2
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
62
P-Site Identity:
100
6.6
100
86.6
N.A.
80
6.6
N.A.
80
6.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
86.6
N.A.
80
33.3
N.A.
80
13.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% C
% Asp:
0
0
0
60
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
60
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
30
0
10
0
% H
% Ile:
50
0
0
0
0
10
0
0
0
10
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
40
10
0
10
0
10
60
0
0
% K
% Leu:
10
50
0
0
20
0
0
0
10
40
20
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
20
60
10
0
10
0
10
10
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
0
10
10
10
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
80
20
0
60
0
% R
% Ser:
0
0
10
20
10
10
0
40
10
10
0
10
20
0
70
% S
% Thr:
0
0
10
0
0
0
0
10
0
10
0
10
0
0
0
% T
% Val:
10
0
0
0
0
10
10
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _